Yup, I know. It's a strange combination haha, but I'm obsessed with finding this movie.
It's about a man and a woman. He most probably is her husband but I'm not sure. I don't remember many details, but all I know is that the alleged husband ends up in a wheelchair (or is on it from the beginning) and they're on a boat sometime during the movie. A man (with some accomplices) rapes the woman several times during the movie. One scene involves them tying her up on a fence and cutting her panties with a knife.
Something else I remember is that in the end, the main bad guy is dying of something I think, and the woman has the antidote, but she drops it on the floor in front of him (inside the boat).