A nature field researcher is investigating the strange extinction of small animals and insects in the area, which indicates that something is wrong. His suspicions are soon to be proven right when he meets May, who lives in a cabin in the forest nearby. May says that her house is infested by small creatures that she thinks are mice or rats. When the couple search the house further, they notice that they're not rodents or insects. They are fast-evolving lizards that have the appetite for animals and humans, no matter what size their prey are.
From IMDb review:
A young girl (Pamela Gidley) escaping her troubled life finds refuge in her family's old house in the mountains. She gets stuck in her house~luckily with a grad student (Simon Bossell) who specializes in animals. Very soon after they get stuck, the showdown with the killer geckos begins. All parts with the geckos are entertaining, but by far the best bit is when the girl's boyfriend (Valeriy Nikolaev) finds where she's hiding and tries to force 'his' money out of her.